vivoPHIX

Next generation biosample stabilization

For tissue fixation, tissue dissociation, biomolecule stabilization & scRNA-seq applications

vivoPHIX

Core features

vivoPHIX is a patented next generation tissue fixation and biomolecule stabilizer compatible with all biological sample types. vivoPHIX has been tested by over 180 researchers worldwide.

Cell & Tissue Fixation

  • Cellular morphology of fresh & fresh frozen tissue is conserved
  • Samples can be embeded in paraffin for staining
  • Compatible with GFP detection, IF, IHC, ISH and RNAscope imaging

RNA, DNA & Protein Stabilization

  • Long-term biomolecule stabilization
  • Substantially improves RNA and DNA quality compared to competing products
  • Compatible with front-end RNA purification kits even when the sample is blood

Tissue Dissociation

  • Easy dissociation into individual cells retaining original 3D morphological characteristics with scRNAseq compatibility
  • Ready-to-use protocol for single-cell RNA/Seq
  • Can be used for 16S NGS and WTA metagenomics

Virus, Bacteria & Yeast Inactivation

  • Inactivates viruses, bacteria & yeast
  • Easy storage & transportation of sensitive samples
  • Stabilises human viral nucleic acid for over 6 months

Safe Handling

  • No hood : carcinogen-free & low volatility reagent unlike formaldehyde
  • Partially degradable
  • Room temperature use

Room-Temperature

Storage & Logistics

  • Easy collection & transportation of samples from resource-poor setting to testing lab
  • Improves laboratory throughput, logistics
  • Allows samples to be collected over days or weeks for processing as a single-batch

vivoPHIX

Applications

vivoPHIX is a patented next generation tissue fixation and biomolecule stabilizer compatible with all biological sample types. vivoPHIX has been tested by over 180 researchers worldwide.

Immunofluorescence

in situ hybridization

Single-cell analysis

vivoPHIX

180 evaluators worldwide

vivoPHIX is a patented next generation tissue fixation and biomolecule stabilizer compatible with all biological sample types. vivoPHIX has been tested by over 180 researchers worldwide.

``It’s working amazingly for my project``

Sanger Institute

``The signals are very good``

University of Cambridge

``RNAssist samples have more reads per cell ... single cell libraries are better with RNAssist than without”

Sanger Institute

``I think the RNAssist is an amazing technology with important applications for us. And the results are quite amazing``

University of Calgary

``What I am seeing is that RNA quality is very high. The quality was higher than the corresponding methanol fixed tumour``

University of Oxford

`` we have beautiful results in histopathology and similar beautiful IHC ``

CFIA

``I can tell you that RNAssist is very good for storage of fixed tissue samples and further histological staining with hematoxilin and Eosin``

University of Rome

``Very impressed by results``

Pasteur Institute

vivoPHIX

Latest News

Contact us

If you would like to receive news about RNAssist and associated products, evaluate our ground-breaking fixative and stabiliser, carryout tissue dissociation and single-cell preparation or would simply like to exchange comments and results with more than 180 other members of the RNAssist User Community please send a message. We look forward to meeting you!

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RNAssist is a universal tissue fixation and RNA stabilization reagent.

This non-toxic formalin-free tissue fixative ensures the preservation of both tissue histomorphology and biomolecules. RNAssist prevents the degradation of proteins, DNA, RNA and mRNA. When compared to products such as RNAlater ®, PAXgene Tissue Systems or Allprotect ® Tissue Reagent, RNA demonstrated high-quality RNA stabilization and protection in the context of long-term tissue storage and archival . Designed for room temperature use, RNAssist is compatible with routine paraffin-embedding procedure, pathology staining – (H&E, immunohistochemistry (IHC) , in situ hybridization (IS) – and molecular analysis : RT-PCR, WB, next-geneneration sequencing, …