TheraPHIX™, vivoPHIX™, genoPHIX™ and virusPHIX™
RNAssist Blog
RNAssist and Fiocruz collaborate on TheraPHIX™ project in BrazilAndrew Goldsborough - our CEO, recently visited Rio de Janeiro, Brazil, to meet with the team at Fiocruz / Bio-Manguinhos as part of a joint project focused on TheraPHIX™, RNAss...
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RNAssist at the RNA Vaccines and Therapeutics Conference 2025Our CEO, Andrew Goldsborough, will be attending the RNA Vaccines and Therapeutics Conference in London on 23–24 September 2025. Hosted by CPI at the Royal College of Physicians,...
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vivoPHIX™-enabled platform published in Cell Reports reveals new insights into Th17 biologyA new study published in Cell Reports (August 2025) demonstrates how RNAssist’s vivoPHIX™ fixative underpins a powerful new technique — Vivo-seq — enabling simultaneous single-c...
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High-quality single-cell RNA-seq from insect midguts — enabled by vivoPHIX™Single-cell RNA sequencing relies on clean, intact RNA — but most dissociation protocols for insect tissues involve enzymatic digestion and heat, both of which distort the trans...
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We're attending the UK Clinical Vaccine Network Conference 2025Are you ready to leave freezer logistics behind? Thursday 12 June at the UK Clinical Vaccine Network Conference, our CEO, Dr Andrew Goldsborough, will unveil TheraPHIX™—an ambie...
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TheraPHIX™: Enabling global vaccine equity with thermostable RNA formulationsThe rapid development of RNA vaccines during the COVID-19 pandemic saved millions of lives. However, one major challenge remains: RNA degrades quickly when exposed to heat, enzy...
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RNAssist is attending the World Vaccine CongressJoin us at the World Vaccine Congress next week as we showcase our latest breakthrough in mRNA-LNP stability, TheraPHIX™!We’re thrilled that our CEO, Andrew Goldsborough will be...
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Introducing TheraPHIX™ our thermostabilization breakthroughRNAssist is proud to announce the development of TheraPHIX™, a pioneering solution for mRNA vaccine and therapeutic stability. In collaboration with the Centre for Process Innov...
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ImmunofluorescencegenoPHIX™ is for fixing and paraffin embedding tissue sections for a variety of histology applications including H&E staining, ISH, FISH, IHC and Immunofluorescence. Because our...
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In Situ Hybridization (ISH)RNAssist fixed mouse liver, paraffin embedded, stained with RNAscope® probe PPIB.Thanks to Bingqing Zhang, ACD™, Bio-techne.in situ hybridisation of Liver sections using a Venta...
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Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signaling in Single-Cell SequencingSingle-cell RNA sequencing presents an opportunity to deconstruct cellular networks but is limited by the loss of biological information. In this study, a new method of fixation...
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Taking Insect Immunity to the Single-Cell LevelThis research paper used the RNAssist’s vivoPHIX™ system to examine the intricacies of insect innate immunity.Sarah Merkling et al., aimed to gain a deeper understanding of the...
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Influenza AAn Influenza A expert working at the Pasteur Institute has demonstrated and had approved a protocol for the inactivation of Influenza A virus (plaque forming assay with A549 cel...
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Using vivoPHIX™ to stabilise bacteria from carnivorous plants in the junglevivoPHIX has many applications – wherever your research may take you. Here are some photos from a recent project in South East Asia, where we were collecting bacteria from carni...
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Determination and localisation of Lanosterol Synthase in human cataractous lenses and their relationship with αA crystallin proteinsDr Avila’s laboratory has used vivoPHIX™ to prepare human cataract crystallin proteins. The study aimed to determine the expression of Lanosterol Synthase in human cataractous l...
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Stabilization of HCV plasmaTwo strains of HCV in human plasma was stored either for 6 months at -80°C or, mixed with vivoPHIX and stored for 6 months at 20°C prior to HCV RNA extraction (Nucleosens) and R...
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Stabilization of RNA in Botanical SamplesExtraction of total RNA from palm (Chamaedorea geonomiformis) inflorescence using vivoPHIX reagent in conjunction with a Qiagen RNeasy-plant kit; comparison with results obtaine...
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RNAssist reagents have been delivered and used onboard the International Space StationWe are delighted to report that this week RNAssist reagents will be combined with various biological samples aboard the International Space Station in the microgravity condition...
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RNAssist stabilisation reagents published in the Biopreservation and Biobanking Journal (2019) for microbiome analysisWe are proud to have provided RNAssist reagents to the laboratory of Dr. Fay Betsou and Dr. Lorie Neuberger-Castillo at the Integrated Biobank of Luxembourg (IBBL) and pleased t...
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RNAssist sponsors the 23rd Genomic Standards Consortium MeetingWe are delighted to announce that we are sponsoring The Genomic Standards Consortium (GSC)’s 23rd meeting. The meeting will be held in Bangkok, Thailand, from August 7th to 11th...
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Partnering with a pan European nematode group, NERVSPANWe are delighted to be a partner for the EU-funded NERVSPAN research community that will develop an integrative approach to study various aspects of neuronal physiology througho...
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Expression of oxysterols in human lenses: Implications of the sterol pathway in age-related cataractsLanosterol is implicated in cataract formation – it has been proposed to help maintain lens transparency by inhibiting the formation of protein aggregates. Their data confirms t...
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Two of RNAssist’s molecular stabilsation reagents will be taken to the International Space StationWe are delighted that we can make a small contribution to the important work of Dr. Scott Tighe, Technical Director at the Advanced Genomics Lab at the University of Vermont, NA...
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RNAssist announces new manufacturing & supply agreement with Rapid LabsRNAssist and Rapid Labs Agree on Manufacturing and Supply Agreement for genoPHIX™ and vivoPHIX™ Biomolecule Stabilisation, Tissue Fixation and Microbial Inactivation Technology....
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Profiling the Microbial Communities of Brooks Cave in Pennington County, South DakotaStudies on cave bacteria have been a valuable research area in both geology and biology, providing insights into the evolution of antibiotic resistance, the role of microbes in...
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Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other ApplicationsLoop-mediated isothermal amplification (LAMP) has played a crucial role in filling global COVID-19 testing need. ln this study, Moore et al., discuss the use of virusPHIX™ for t...
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Daily rhythms in gene expression of the human parasite Schistosoma mansoniKate Rawlinson at the Sanger Institute, Hinxton, UK used vivoPHIX™ to preserve RNA of the Schistosome parasite for a ‘circadian clock study’. Due to the Earth’s natural rotation...
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Tools for connectomics in C.elegansNicholas Barry at the MIT Media Lab used vivoPHIX™ for preparing nematodes for fluorescence studies in work titled “Tools for connectomics in C.elegans“The simplicity of the 302...
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We’re attending the mRNA – Based Therapeutics SummitWe are delighted to attend the 2nd Annual mRNA-Based Therapeutics Summit 24th-26th January 2023 in Berlin. Following the successful development of vaccines against Covid-19, bio...
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Virucidal efficacy of guanidine-free inactivants and rapid test buffers against SARS-CoV-2In this paper, Killip et al., (Public Health England) have used RNAssist’s virusPHIX™ reagents to demonstrate SARS-CoV-2 inactivation. We were asked by the UK Department for Hea...
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Importance of external quality assessment for SARS-CoV-2 antigen detection during the COVID-19Mantke et al., demonstrated the use of virusPHIX-P9™ for stablising SARS-CoV-2 Antigen and use by 258 participants across 27 countries for Lateral flow rapid antigen tests, auto...
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QCMD to use RNAssist’s virusPHIX-P9™ Biomolecule Stabilization Technology in its SARS-CoV-2 antigen EQA schemeIn a further development of the collaboration between QCMD and RNAssist, QCMD will use the universal biological sample stabilization virusPHIX-P9™ as the matrix within its forth...
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RNAssist Limited and QCMD Agree Collaboration for vivoPHIX™ Biomolecule Stabilization TechnologyCambridge and Glasgow, UK. 23rd January 2020 – RNAssist. (www.RNAssist.com) a UK company that has developed a universal biological sample stabilization, fixation and inactivatio...
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