TheraPHIX™, vivoPHIX™, genoPHIX™ and virusPHIX™
RNAssist Stories
RNAssist’s products have been used all over the world, both in leading research laboratories and out in the field, including for biosampling during caving expeditions, aboard marine research boats and in tropical forests.
The extensive range of its applications for these products is attributable to their universal and powerful biomolecule stabilisation properties, safety during transportation and a myriad of other unique properties such as their microbicide activity, cell and tissue fixation capability (even with frozen-tissues), compatibility with multiple front-end nucleic-acid purification platforms (RNeasy®, QIAcube®, QIAsymphony®, FilmArray®, Nucleosens®..) and multiple supporting protocols generated by the RNAssist user community.
Next generation biosample stabilization
In the lab, vivoPHIX™ has been used to treat a wide range of samples including tissue culture cells, human parasites including Schistosomes, Trypanosomes and Plasmodium, viruses, bacteria, fungi, plants, model organisms including Drosophila and Nematodes and varied clinical samples.
That's not all.... here's where our technology has been used so far:
In the air
vivoPHIX™ has been used to stabilise blood from bats in France, and whole mosquitoes for storage and transport from East Africa to the UK and USA.
In the sea
vivoPHIX™ has been used to stabilise marine filtrates including bacteria collected in the Malacca Straights and in the North Sea for metagenomic analysis.
On the ground
vivoPHIX™ has been used to fix dwarf palm (Chamaedorea geonomiformis) flower samples & stabilise RNA content for downstream applications.
At the farm
vivoPHIX™ has been used to fix bovine brain for BSE testing including IF, IHC and Western blotting.
At the hospital
vivoPHIX™ has been used to fix and stabilise various clinical samples including human colon and pancreatic cancer samples.
Underground
vivoPHIX™ has been taken on a microbial collecting expedition to deep underground lakes in South Dakota for subsequent metagenomics analysis.
Immunofluorescence
genoPHIX™ is for fixing and paraffin embedding tissue sections for a variety of histology applications including H&E staining, ISH, FISH, IHC and Immunofluorescence.
In Situ Hybridization (ISH)
RNAssist fixed mouse liver, paraffin embedded, stained with RNAscope® probe PPIB. Thanks to Bingqing Zhang, ACD™, Bio-techne.
Influenza A
An Influenza A expert working at the Pasteur Institute has demonstrated and had approved a protocol for the inactivation of Influenza A virus (plaque forming assay with A549 cells) using vivoPHIX.
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TheraPHIX™, vivoPHIX™, genoPHIX™, virusPHIX™ and virusPHIX-P9™ are patented next generation cell and tissue fixatives, biomolecule stabilisers with powerful virus and bacterial inactivation properties.
Our reagents are universally compatible with all sample types including viruses, bacteria, fungi, parasites, plants and animal cells and tissues. Both liquid and solid samples are rapidly and completely rendered fixed, stabilised and inactivated.
RNAssist technology supports a wide range of life science applications, including tissue fixation and dissociation, single-cell multiomics (scRNA-seq, CITE-seq), and virus inactivation and transport for enhanced diagnostic testing.
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