TheraPHIX™, vivoPHIX™, genoPHIX™ and virusPHIX™

RNAssist Blog

Featured Research · 30 July 2025vivoPHIX™-enabled platform published in Cell Reports reveals new insights into Th17 biology

A new study published in Cell Reports (August 2025) demonstrates how RNAssist’s vivoPHIX™ fixative underpins a powerful new technique — Vivo-seq — enabling simultaneous single-c...

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Featured Research · 20 July 2025High-quality single-cell RNA-seq from insect midguts — enabled by vivoPHIX™

Single-cell RNA sequencing relies on clean, intact RNA — but most dissociation protocols for insect tissues involve enzymatic digestion and heat, both of which distort the trans...

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Featured Research · 16 August 2024Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signaling in Single-Cell Sequencing

Single-cell RNA sequencing presents an opportunity to deconstruct cellular networks but is limited by the loss of biological information. In this study, a new method of fixation...

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Featured Research · 16 August 2024Taking Insect Immunity to the Single-Cell Level

This research paper used the RNAssist’s vivoPHIX™ system to examine the intricacies of insect innate immunity.Sarah Merkling et al., aimed to gain a deeper understanding of the...

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Featured Research · 7 August 2024Determination and localisation of Lanosterol Synthase in human cataractous lenses and their relationship with αA crystallin proteins

Dr Avila’s laboratory has used vivoPHIX™ to prepare human cataract crystallin proteins. The study aimed to determine the expression of Lanosterol Synthase in human cataractous l...

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Featured Research · 8 August 2023RNAssist stabilisation reagents published in the Biopreservation and Biobanking Journal (2019) for microbiome analysis

We are proud to have provided RNAssist reagents to the laboratory of Dr. Fay Betsou and Dr. Lorie Neuberger-Castillo at the Integrated Biobank of Luxembourg (IBBL) and pleased t...

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Featured Research · 12 July 2023Expression of oxysterols in human lenses: Implications of the sterol pathway in age-related cataracts

Lanosterol is implicated in cataract formation – it has been proposed to help maintain lens transparency by inhibiting the formation of protein aggregates. Their data confirms t...

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Featured Research · 8 February 2023Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications

Loop-mediated isothermal amplification (LAMP) has played a crucial role in filling global COVID-19 testing need. ln this study, Moore et al., discuss the use of virusPHIX™ for t...

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Featured Research · 7 February 2023Daily rhythms in gene expression of the human parasite Schistosoma mansoni

Kate Rawlinson at the Sanger Institute, Hinxton, UK used vivoPHIX™ to preserve RNA of the Schistosome parasite for a ‘circadian clock study’. Due to the Earth’s natural rotation...

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Featured Research · 7 February 2023Tools for connectomics in C.elegans

Nicholas Barry at the MIT Media Lab used vivoPHIX™ for preparing nematodes for fluorescence studies in work titled “Tools for connectomics in C.elegans“The simplicity of the 302...

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Featured Research · 16 August 2022Virucidal efficacy of guanidine-free inactivants and rapid test buffers against SARS-CoV-2

In this paper, Killip et al., (Public Health England) have used RNAssist’s virusPHIX™ reagents to demonstrate SARS-CoV-2 inactivation. We were asked by the UK Department for Hea...

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Featured Research · 11 August 2021Importance of external quality assessment for SARS-CoV-2 antigen detection during the COVID-19

Mantke et al., demonstrated the use of virusPHIX-P9™ for stablising SARS-CoV-2 Antigen and use by 258 participants across 27 countries for Lateral flow rapid antigen tests, auto...

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