the solution to a universal industry problem
Major deficiencies of current Virus Transport Media (VTM’s) are that they are variously toxic, incompletely inactivate viruses or are poor stabilisers of RNA and proteins, precluding their use for home-testing, transport, storage and safe handling.
We have completed development of a solution that uniquely allows the inactivation and preservation of viruses at the point of sampling, whatever the virus and whatever the downstream application. Uniquely, virusPHIX™ is compatible with both nucleic acid (e.g. PCR) and antigen (e.g. Ag lateral flow) based SARS-CoV-2 tests. This buffer also slots faultlessly into your workflow as follows.
Simultaneously inactivates and preserves clinical samples in one easy step
Completely inactivates >10log7 SARS-CoV-2 in 10 minutes at 20°C
Universal inactivation of 10 tested viruses (Pasteur Institute, CDC, BlueTest)
Kills 3 clinical strains of Mycobacterium tuberculosis in 10 minutes (WEHI)
Direct to LAMP and Lateral Flow assay compatibility (Qnostics UK)
Validated with 8 different SARS-CoV-2 lateral flow assays (Qnostics UK)
Stabilises SARS-CoV-2 Antigen for at least 6 weeks (Qnostics, UK)
Robust SARS-CoV-2 RNA stabilisation for 42 days (Qnostics)
Demonstrated HCV RNA stabilisation for 1 year at 20°C Universal sample compatibility including swabs and saliva
Proven 100 copy LOD using ThermoFisher KingFisher™ and bioMerieux Nuclisens™
Effortless integration with front-end nucleic acid purification platforms including RNeasy™, QIAsymphony™, QIAcube™, Nuclisens™, GeneXpert™ and Filmarray™
Tested by UK Lighthouse SARS-CoV-2 testing laboratories
Facilitates safe logistics via ambient temperature shipping and storage
Contains no formaldehyde, chaotropes, alcohol or other hazardous chemicals
Green and very low toxicity (LD50 >20g/kg), low volatility and non-flammable
1-month 20°C Stabilisation of West Nile Virus and SARS-CoV-2 RNA in Sputum using virusPHIX™ (QIAamp purification and RT-qPCR)
42 Days SARS-CoV-2 RNA Stabilisation at 20°C or 37°C using virusPHIX-P9™
1-Year 20°C Stabilisation of 2 Strains of HCV in Plasma using virusPHIX™
RT-qPCR Limit of Detection (LOD) Study of SARS-CoV-2 in aqueous buffer compared with Inactivating Buffer virusPHIX™ (1-week stabilisation at 20°C)
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vivoPHIX™, genoPHIX™, virusPHIX™ and virusPHIX-P9™ are patented next generation cell and tissue fixatives, biomolecule stabilisers with powerful virus and bacterial inactivation properties.
Our reagents are universally compatible with all sample types including viruses, bacteria, fungi, parasites, plants and animal cells and tissues. Both liquid and solid samples are rapidly and completely rendered fixed, stabilised and inactivated.
RNAssist technology supports a wide range of life science applications, including tissue fixation and dissociation, single-cell multiomics (scRNA-seq, CITE-seq), and virus inactivation and transport for enhanced diagnostic testing.
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